Illudalic acid, CAS 18508-77-5

Product Description: Illudalic acid is a potent and selective Leukocyte antigen-related (LAR) phosphatase inhibitor with an IC50 value of 1.30 µM. Illudalic acid inhibits LAR phosphatase through covalent ligation to the catalytic cysteine residue[1][2].

Formula: C15H16O5

References: [1]Hansen DT, et al. The mechanism of covalent inhibition of LAR phosphatase by illudalic acid. Bioorg Med Chem Lett. 2024 May 15;104:129740./[2]Ling Q, et al. Illudalic acid as a potential LAR inhibitor: synthesis, SAR, and preliminary studies on the mechanism of action. Bioorg Med Chem. 2008 Aug 1;16(15):7399-409.

CAS Number: 18508-77-5

Molecular Weight: 276.28

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Phosphatase

• SKU: MEXHY-N12776-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N12776-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK