IMPDH2-IN-2, CAS 1434517-02-8

Product Description: IMPDH2-IN-2 is a potent inhibitor of inosine 5’-monophosphate dehydrogenase (IMPDH) with a Ki,app value of 14 μM, respectively. IMPDH2-IN-2 displays moderate antibacterial activity (MIC = 6.3 and 11 μM in minimal GAST/Fe and rich 7H9/ADC/Tween media, respectively). IMPDH2-IN-2 is a potential anti-tuberculosis agent[1].

Applications: COVID-19-immunoregulation

Formula: C21H15Cl2N3O3

References: [1]Chacko S, et al. Expanding Benzoxazole-Based Inosine 5'-Monophosphate Dehydrogenase (IMPDH) Inhibitor Structure-Activity As Potential Antituberculosis Agents [published correction appears in J Med Chem. 2021 Dec 23;64(24):18233-18234]. J Med Chem. 2018;61(11):4739-4756.

CAS Number: 1434517-02-8

Molecular Weight: 428.27

Research Area: Cancer; Infection

Solubility: 10 mM in DMSO

Target: Bacterial

• SKU: MEXHY-145286-100
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-145286-100
• Green Labware: No
• Package Unit: 100 mg
• Quantity Unit: STK