iNOS/COX-2-IN-1

Product Description: iNOS/COX-2-IN-1 (Compound 12e) is an inhibitor of cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS). iNOS/COX-2-IN-1 inhibits the NF-κB and MAPKs signaling pathways and thus exerts anti-inflammatory effects[1].

Formula: C31H38FN3O2S

References: [1]Cai X, et al. Design, synthesis and molecular modeling of novel D-ring substituted steroidal 4,5-dihydropyrazole thiazolinone derivatives as anti-inflammatory agents by inhibition of COX-2/iNOS production and down-regulation of NF-κB/MAPKs in LPS-induced RAW264.7 macrophage cells. Eur J Med Chem. 2024 Apr 27;272:116460.

Molecular Weight: 535.72

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: COX;NO Synthase

• SKU: MEXHY-161513-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-161513-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK