IOX5

Product Description: IOX5 is a selective prolyl hydroxylases (PHD) inhibitor. IOX5 stabilizes HIF-1α in AML cells, induces apoptosis, and upregulates BNIP3 expression. IOX5 compromises development and progression of acute myeloid leukemia[1].

Applications: Cancer-programmed cell death

Formula: C17H19F3N4O2

References: [1]Lawson H, et al. The selective prolyl hydroxylase inhibitor IOX5 stabilizes HIF-1α and compromises development and progression of acute myeloid leukemia. Nat Cancer. 2024 Apr 18.

Molecular Weight: 368.35

Research Area: Cancer

Target: Apoptosis;HIF/HIF Prolyl-Hydroxylase

• SKU: MEXHY-158341-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-158341-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK