Ir-UA, CAS 3033235-42-3

Product Description: Ir-UA is an usnic acid-derived iridium(III) complex that enhances PD-L1 expression and converts "cold tumors" into "hot tumors." Ir-UA stimulates PD-L1 expression by explicitly regulating the PD-L1 transcription factor[1].

Formula: C52H43F6IrN5O6P 2+

References: [1]Deng D, et al. Iridium(III)-Based PD-L1 Agonist Regulates p62 and ATF3 for Enhanced Cancer Immunotherapy. J Med Chem. 2024 Apr 25;67(8):6810-6821.

CAS Number: 3033235-42-3

Molecular Weight: 1171.11

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: PD-1/PD-L1

• SKU: MEXHY-162463-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-162463-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK