Irinotecan, CAS 97682-44-5

Description: Irinotecan (CPT-11), a derivative of camptothecin, is an inhibitor of DNA topoisomerase I (Topo I). Irinotecan has antitumor activity by preventing DNA strand reattachment through binding to the Topo I complex, resulting in double-stranded DNA breaks and cell death.

CAS Number: 97682-44-5

Formula: C33H38N4O6

Molecular Weight: 586,68

References: Keyvani-Ghamsari S, et al. Effect of irinotecan on HMGB1, MMP9 expression, cell cycle, and cell growth in breast cancer (MCF-7) cells. Tumour Biol. 2017 Apr;39(4):1010428317698354.

• SKU: TGMT6228-1mL
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T6228-1mL
• Package Unit: 1 mL
• Quantity Unit: STK