Izonsteride, CAS 176975-26-1

Product Description: Izonsteride (Compound LY320236) is an inhibitor of 5α-reductase (IC50 = 11.6 nM for type I; 7.37 nM for type II). LY320236 inhibits the activity of steroid 5α-reductase, preventing the conversion of testosterone (T) to dihydrotestosterone (DHT). LY320236 can significantly inhibit the growth of LNCaP tumors in thymic mice without exhibiting obvious host toxicity[1].

Applications: Metabolism-sugar/lipid metabolism

Formula: C24H26N2OS2

References: [1]McNulty AM, et al. Kinetic analysis of LY320236: competitive inhibitor of type I and non-competitive inhibitor of type II human steroid 5alpha-reductase. J Steroid Biochem Mol Biol. 2000 Jan-Feb;72(1-2):13-21.

CAS Number: 176975-26-1

Molecular Weight: 422.61

Research Area: Cancer; Endocrinology

Solubility: 10 mM in DMSO

Target: 5 alpha Reductase

• SKU: MEXHY-106129-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-106129-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK