IZTZ-1, CAS 2636771-45-2

Product Description: IZTZ-1, an imidazole-benzothiazole conjugate, is a c-MYC G4 ligand. IZTZ-1 is able to downregulate the c-MYC expression by stabilizing c-MYC G4. IZTZ-1 induces cell cycle arrest, apoptosis, thereby inhibiting cell proliferation in B16 cells. IZTZ-1 shows antitumor activity, and can be used for melanoma research[1].

Applications: Cancer-programmed cell death

Formula: C32H35N7S

References: [1]Wu TY, et al. A drug-like imidazole-benzothiazole conjugate inhibits malignant melanoma by stabilizing the c-MYC G-quadruplex. Bioorg Chem. 2020 Jun;99:103866.

CAS Number: 2636771-45-2

Molecular Weight: 549.73

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Apoptosis;c-Myc

• SKU: MEXHY-147973-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-147973-25
• Green Labware: No
• Package Unit: 25 mg
• Quantity Unit: STK