JYQ-164

Product Description: JYQ-164 is a small molecule inhibitor of Parkinson's disease protein 7 (PARK7/DJ-1) in humans. JYQ-164 works by covalently and selectively targeting Cys106, a key residue of PARK7 (IC50=21 nM). The high inhibitory effect of JYQ-164 on PARK7 is 5 times more potent than the previously reported inhibitor JYQ-88. JYQ-164 can be used in Parkinson's disease and cancer research[1].

Formula: C23H26N6O5S2

References: [1]Jia Y, et al. Development of Inhibitors, Probes, and PROTAC Provides a Complete Toolbox to Study PARK7 in the Living Cell[J]. Journal of Medicinal Chemistry, 2024.

Molecular Weight: 530.62

Research Area: Cancer; Neurological Disease

Target: Others

• SKU: MEXHY-163562-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-163562-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK