Kallikrein 5-IN-2 (TFA)

Product Description: Kallikrein 5-IN-2 TFA is the TFA salt form of Kallikrein 5-IN-2 (HY-148949). Kallikrein 5-IN-2 TFA is a selective inhibitor for kallikrein 5 (KLK5) with pIC50 of 7.1. Kallikrein 5-IN-2 TFA is non-phototoxic (100 μg/mL) and non-irritant. Kallikrein 5-IN-2 is stable at pH 4-pH 8 under non-oxidative condition. Kallikrein 5-IN-2 is potent in ameliorating the Netherton syndrome[1].

Formula: C25H23F3N6O3

References: [1]Walker AL, et al. Structure guided drug design to develop kallikrein 5 inhibitors to treat Netherton syndrome. Bioorg Med Chem Lett. 2019 Jun 15;29(12):1454-1458.

Molecular Weight: 512.48

Research Area: Others

Target: Kallikrein

• SKU: MEXHY-148949A-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-148949A-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK