KDM5B ligand 2

Product Description: KDM5B ligand 2 is the ligand for target protein KDM5B. KDM5B ligand 2 is utilized for synthesis of KDM5B PROTAC GT-653 (HY-158432)[1].

Formula: C15H10N4O4

References: [1]Guan T, et al., Discovery of an efficacious KDM5B PROTAC degrader GT-653 up-regulating IFN response genes in prostate cancer. Eur J Med Chem. 2024 May 10;272:116494. 

Molecular Weight: 310.26

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Histone Demethylase;Ligands for Target Protein for PROTAC

• SKU: MEXHY-158433-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-158433-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK