Keap1-Nrf2-IN-20

Product Description: Keap1-Nrf2-IN-20 (Compound ZC9) is an inhibitor for Keap-Nrf2 pathway with KD2 of 51 nM. Keap1-Nrf2-IN-20 exhibits good cell permeability, cell activity, and metabolic stability (serum t1/2 > 24 h)[1].

Applications: COVID-19-immunoregulation

Formula: C42H67N11O19

References: [1]Zou J, et al., Cyclic Peptide Keap1-Nrf2 Protein-Protein Interaction Inhibitors: Design, Synthesis, and In Vivo Treatment of Acute Lung Injury. J Med Chem. 2024 Mar 28;67(6):4889-4903.

Molecular Weight: 1030.04

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: Keap1-Nrf2

• SKU: MEXHY-158055-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-158055-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK