Product Description: KSL 128114, a peptide inhibitor of syntenin, binds the PDZ1 domain of syntenin with nanomolar affinity. KSL 128114 is resistant toward degradation in human plasma and mouse hepatic microsomes and displays a global PDZ domain selectivity for syntenin[1].
Formula: C96H165N39O21
References: [1]Linda M Haugaard-Kedström, et al. A High-Affinity Peptide Ligand Targeting Syntenin Inhibits Glioblastoma. J Med Chem. 2021 Feb 11;64(3):1423-1434.