KTC1101, CAS 2764833-47-6

Product Description: KTC1101 is an orally active pan-PI3K inhibitor. KTC1101 can inhibit the PI3K signaling pathway, reduce downstream AKT and mTOR phosphorylation, and reduces the expression of Ki67. The anti-tumor effect of KTC1101 has a dual mechanism of action: directly inhibiting tumor cell growth and dynamically enhancing immune response[1].

Formula: C21H26F2N8O3

References: [1]Peng X, et al. A novel pan-PI3K inhibitor KTC1101 synergizes with anti-PD-1 therapy by targeting tumor suppression and immune activation. Mol Cancer. 2024 Mar 14;23(1):54.

CAS Number: 2764833-47-6

Molecular Weight: 476.48

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Akt;mTOR;PI3K

• SKU: MEXHY-162382-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-162382-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK