LCH-7749944, CAS 796888-12-5

Product Description: LCH-7749944 (GNF-PF-2356) is a potent PAK4 inhibitor with an IC50 of 14.93 μM. LCH-7749944 effectively suppresses the proliferation of human gastric cancer cells through downregulation of PAK4/c-Src/EGFR/cyclin D1 pathway and induces apoptosis[1].

Applications: Cancer-Kinase/protease

Formula: C20H22N4O2

References: [1]Zhang J, et al. LCH-7749944, a novel and potent p21-activated kinase 4 inhibitor, suppresses proliferation and invasion in human gastric cancer cells. Cancer Lett. 2012 Apr 1;317(1):24-32.

CAS Number: 796888-12-5

Molecular Weight: 350.41

Compound Purity: 99.36

Research Area: Cancer

Solubility: DMSO : 250 mg/mL (ultrasonic)

Target: Apoptosis;PAK

• SKU: MEXHY-125035-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-125035-25
• Green Labware: No
• Package Unit: 25 mg
• Quantity Unit: STK