Lenalidomide-5-aminomethyl (hydrochloride), CAS 1158264-69-7

Product Description: Lenalidomide-5-aminomethyl hydrochloride is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-5-aminomethyl hydrochloride can be connected to the ligand for protein by a linker to form PROTAC[1]

Applications: Cancer-programmed cell death

Formula: C14H16ClN3O3

References: [1]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985./[2]Scheepstra M, et al. Bivalent Ligands for Protein Degradation in Drug Discovery. Comput Struct Biotechnol J. 2019;17:160-176. Published 2019 Jan 25.

CAS Number: 1158264-69-7

Molecular Weight: 309.75

Compound Purity: 99.73

Research Area: Cancer

Solubility: DMSO : 16.67 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Ligands for E3 Ligase

• SKU: MEXHY-W077589-250
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W077589-250
• Green Labware: No
• Package Unit: 250 mg
• Quantity Unit: STK