Lenalidomide-I, CAS 2207541-30-6

Product Description: Lenalidomide-I (Compound 72), an analog of cereblon (CRBN) ligand Lenalidomide for E3 ubiquitin ligase, is used in the recruitment of CRBN protein. Lenalidomide-I can be connected to the ligand for protein by a linker to form PROTACs, such as the PROTAC BET degrader QCA570 (HY-112609)[1].

Applications: Cancer-programmed cell death

Formula: C13H11IN2O3

References: [1]Qin C, et, al. Discovery of QCA570 as an Exceptionally Potent and Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of the Bromodomain and Extra-Terminal (BET) Proteins Capable of Inducing Complete and Durable Tumor Regression. J Med Chem. 2018 Aug 9;61(15):6685-6704.

CAS Number: 2207541-30-6

Molecular Weight: 370.14

Compound Purity: 99.90

Research Area: Cancer

Solubility: DMSO : 25 mg/mL (ultrasonic)

Target: Ligands for E3 Ligase

• SKU: MEXHY-131318-250
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-131318-250
• Green Labware: No
• Package Unit: 250 mg
• Quantity Unit: STK