Lersivirine, CAS 473921-12-9

Product Description: Lersivirine (UK-453061) is potent and selective non-nucleoside reverse transcription inhibitor (NNRTI; IC50=119 nM) with excellent efficacy against NNRTI-resistant viruses. Lersivirine exhibits potent antiretroviral activity against wild-type HIV virus and clinically relevant NNRTI-resistant strains[1].

Applications: COVID-19-anti-virus

Formula: C17H18N4O2

References: [1]Gregg D Cappon, et al. Developmental toxicity study of lersivirine in mice. Birth Defects Res B Dev Reprod Toxicol. 2012 Jun;95(3):225-30./[2]Mowbray CE, et al. Pyrazole NNRTIs 4: selection of UK-453,061 (lersivirine) as a development candidate. Bioorg Med Chem Lett. 2009 Oct 15;19(20):5857-60.

CAS Number: 473921-12-9

Molecular Weight: 310.35

Compound Purity: 98.38

Research Area: Infection

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: HIV;Reverse Transcriptase

• SKU: MEXHY-14267-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-14267-25
• Green Labware: No
• Package Unit: 25 mg
• Quantity Unit: STK