Product Description: LM-41 is a Flufenamic acid-derived TEAD inhibitor hat strongly reduce the expression of CTGF, Cyr61, Axl and NF2. LM-41 inhibits migration of human MDA-MB-231 breast cancer cells[1].
Applications: Cancer-programmed cell death
Formula: C19H14FNO2
References: [1]Ahmed Fnaiche, et al. Development of LM-41 and AF-2112, two flufenamic acid-derived TEAD inhibitors obtained through the replacement of the trifluoromethyl group by aryl rings. Bioorg Med Chem Lett. 2023 Oct 15:95:129488.
CAS Number: 2996821-30-6
Molecular Weight: 307.32
Compound Purity: 99.82
Research Area: Cancer
Solubility: DMSO : 140 mg/mL (ultrasonic)
Target: YAP