Product Description: Luzopeptin A (BBM-928 A) is an actinoleukin-like antitumor antibiotic. Luzopeptin A is a bifunctional DNA intercalator which can interact with isolated DNA molecules. Luzopeptin A induces an unwinding-rewinding process of the closed superhelical PM2 DNA. Luzopeptin A is active against HIV-1 and HIV-2 reverse transcriptase with IC50s of 7 nM and 68 nM for HIV-1 RT and HIV-2 RT, respectively[1][2].
Applications: COVID-19-immunoregulation
Formula: C64H78N14O24
References: [1]Konishi M, Ohkuma H, Sakai F, et al. Structures of BBM-928 A, B, and C. Novel antitumor antibiotics from Actinomadura luzonensis[J]. Journal of the American Chemical Society, 1981, 103(5): 1241-1243.
CAS Number: 75580-37-9
Molecular Weight: 1427.38
Research Area: Cancer; Infection
Solubility: 10 mM in DMSO
Target: Antibiotic;HIV