Product Description: MAO-B-IN-30 (compound IS7) is a potent, selective and cross the blood-brain barrier MAO-B inhibitor with IC50 values of 19.176, 0.082 µM for MAO-A and MAO-B, respectively. MAO-B-IN-30 shows antiproliferative activity and non-cytotoxic. MAO-B-IN-30 reduces TNF-alpha, IL-6, NF-kB levels. MAO-B-IN-30 has the potential for the research of Parkinson's disease[1].
Formula: C15H10BrN3O2
References: [1]Kumar S, Oh JM, Prabhakaran P, Awasti A, Kim H, Mathew B. Isatin-tethered halogen-containing acylhydrazone derivatives as monoamine oxidase inhibitor with neuroprotective effect. Sci Rep. 2024 Jan 13;14(1):1264.
CAS Number: 82973-15-7
Molecular Weight: 344.16
Compound Purity: 98.53
Research Area: Inflammation/Immunology; Neurological Disease
Solubility: DMSO : 4.17 mg/mL (ultrasonic;warming;heat to 60°C)
Target: Monoamine Oxidase
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