MCC950 sodium, CAS 256373-96-3

Description: MCC950 sodium (CP-456773 sodium) is a potent and selective inhibitor of the inflammatory vesicle NLRP3 (IC50=7.5 nM in BMDMs; IC50=8.1 nM in HMDMs). MCC950 sodium has no effect on other inflammatory vesicles such as AIM2, NLRC4 or NLRP1.

CAS Number: 256373-96-3

Formula: C20H23N2O5S·Na

Molecular Weight: 426,46

References: Coll RC, et al. A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases. Nat Med. 2015 Mar;21(3):248-55.

• SKU: TGMT6887-10mg
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T6887-10mg
• Package Unit: 10 mg
• Quantity Unit: STK