MDM2-IN-27

Product Description: MDM2-IN-27 targets MDM2 protein (Ki = 0.4 nM). MDM2-IN-27 activates the anti-tumor activity of p53 and induces apoptosis by blocking the negative regulation of p53 by MDM2[1].

Formula: C32H33Cl2N3O4

References: [1]Lin Z, et al. Synthesis and biological evaluation of 4-imidazolidinone-containing compounds as potent inhibitors of the MDM2/p53 interaction. Eur J Med Chem. 2024 Apr 15;270:116366.

Molecular Weight: 594.53

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: MDM-2/p53

• SKU: MEXHY-162432-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-162432-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK