Mitoxantrone, CAS 65271-80-9

Description: Mitoxantrone (mitozantrone) is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication. This agent also binds to topoisomerase II, resulting in DNA strand breaks and inhibition of DNA repair. Mitoxantrone is less cardiotoxic compared to doxorubicin.

CAS Number: 65271-80-9

Formula: C22H28N4O6

Molecular Weight: 444,48

References: Guerriero E, et al. Vitamin C effect on mitoxantrone-induced cytotoxicity in human breast cancer cell lines. PLoS One. 2014 Dec 22;9(12):e115287.

• SKU: TGMT6588-1mL
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T6588-1mL
• Package Unit: 1 mL
• Quantity Unit: STK