MK-2206 dihydrochloride, CAS 1032350-13-2

Description: MK-2206 dihydrochloride (MK-2206 2HCl) is a variant Akt inhibitor that inhibits Akt1, Akt2, and Akt3 (IC50=8/12/65 nM) with orally active, highly potent and selective potency. MK-2206 dihydrochloride exhibits antitumor activity.

CAS Number: 1032350-13-2

Formula: C25H23Cl2N5O

Molecular Weight: 480,39

References: Hirai H, et al. MK-2206, an allosteric Akt inhibitor, enhances antitumor efficacy by standard chemotherapeutic agents or molecular targeted drugs in vitro and in vivo. Mol Cancer Ther. 2010 Jul;9(7):1956-67.

• SKU: TGMT1952-1mL
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T1952-1mL
• Package Unit: 1 mL
• Quantity Unit: STK