ML385, CAS 846557-71-9

Description: ML385 is an NRF2 inhibitor (IC50=1.9 μM) with novelty and specificity. ML385 has anti-inflammatory activity by modulating anti-oxidative stress through the inhibition of NRF2. ML385 also exhibits anti-tumor activity.

CAS Number: 846557-71-9

Formula: C29H25N3O4S

Molecular Weight: 511,59

References: Singh A, et al. Small Molecule Inhibitor of NRF2 Selectively Intervenes Therapeutic Resistance in KEAP1-Deficient NSCLC Tumors. ACS Chem Biol. 2016 Nov 18;11(11):3214-3225.

• SKU: TGMT4360-10mg
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T4360-10mg
• Package Unit: 10 mg
• Quantity Unit: STK