MRTX1133, CAS 2621928-55-8

Description: MRTX1133 is a KRAS G12D inhibitor (KD=0.2 pM) that is potent, selective, and non-covalent. MRTX1133 exhibits inhibitory activity against KRAS G12D-mutated tumors, but not against KRAS wild-type tumors.

CAS Number: 2621928-55-8

Formula: C33H31F3N6O2

Molecular Weight: 600,63

References: Wang X, et al. Identification of MRTX1133, a Noncovalent, Potent, and Selective KRASG12D Inhibitor. J Med Chem. 2022 Feb 24;65(4):3123-3133.

• SKU: TGMT9303-1mg
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T9303-1mg
• Package Unit: 1 mg
• Quantity Unit: STK