mTOR inhibitor-10, CAS 1144075-36-4

Product Description: mTOR inhibitor-10 (Compound 9c) is a selective inhibitor for mTOR. mTOR inhibitor-10 inhibits mTOR and PI3K-α, with IC50 of 0.7 and 825 nM. mTOR inhibitor-10 inhibits proliferation of LNCaP with IC50 of 87 nM[1].

Formula: C21H22FN5O2S

References: [1]Verheijen JC, et al., Discovery of 2-arylthieno[3,2-d]pyrimidines containing 8-oxa-3-azabi-cyclo[3.2.1]octane in the 4-position as potent inhibitors of mTOR with selectivity over PI3K. Bioorg Med Chem Lett. 2010 Jan 1;20(1):375-9.

CAS Number: 1144075-36-4

Molecular Weight: 427.50

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: mTOR;PI3K

• SKU: MEXHY-162023-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-162023-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK