mTOR inhibitor-23, CAS 1685280-21-0

Product Description: mTOR inhibitor-23 (compound DHM25) is a selective, competitive, irreversible and covalent inhibitor of mTOR. mTOR inhibitor-23 has the mechanism of inhibition occurs mainly through its capacity to covalently interact with a nucleophilic amino acid inside the ATP pocket. mTOR inhibitor-23 exerts potent antitumor activity against triple-negative breast tumor cell lines[1].

Applications: Cancer-Kinase/protease

Formula: C15H8Br3NO3

References: [1]Amélie Fouqué, et al. A Novel Covalent mTOR Inhibitor, DHM25, Shows in Vivo Antitumor Activity against Triple-Negative Breast Cancer Cells. J Med Chem. 2015 Aug 27;58(16):6559-73.

CAS Number: 1685280-21-0

Molecular Weight: 489.94

Research Area: Cancer

Target: mTOR

• SKU: MEXHY-18953-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-18953-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK