Product Description: N-Carbethoxy-4-piperidone is a metabolite of Loratadine (HY-17043). Loratadine is a selective inverse peripheral histamine H1-receptor agonist, and shows anti-dengue-virus (DENV) activity[1][2][3].
Applications: Metabolism-protein/nucleotide metabolism
Formula: C8H13NO3
References: [1]Iesce MR, et al. Ecotoxic effects of loratadine and its metabolic and light-induced derivatives. Ecotoxicol Environ Saf. 2019 Apr 15;170:664-672./[2]Kay GG, et al. Loratadine: a non-sedating antihistamine. Review of its effects on cognition, psychomotor performance, mood and sedation. Clin Exp Allergy. 1999 Jul;29 Suppl 3:147-50./[3]Menardo JL, et al. A review of loratadine in the treatment of patients with allergic bronchial asthma. Clin Ther. 1997 Nov-Dec;19(6):1278-93; discussion 1523-4./[4]Monroe EW. Loratadine in the treatment of urticaria. Clin Ther. 1997 Mar-Apr;19(2):232-42.
CAS Number: 29976-53-2
Molecular Weight: 171.19
Compound Purity: 99.88
Solubility: 10 mM in DMSO
Target: Drug Metabolite
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