N33-TEG-COOH, CAS 201467-81-4

Product Description: N33-TEG-COOH (N3-TEG-COOH) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. N33-TEG-COOH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

Applications: Cancer-programmed cell death

Formula: C10H19N3O6

References: [1]Zengerle M, et al. Selective Small Molecule Induced Degradation of the BET Bromodomain Protein BRD4. ACS Chem Biol. 2015 Aug 21;10(8):1770-7.

CAS Number: 201467-81-4

Molecular Weight: 277.27

Compound Purity: 98.08

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)/Ethanol : 100 mg/mL (ultrasonic)

Target: PROTAC Linkers

• SKU: MEXHY-108370-500
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-108370-500
• Green Labware: No
• Package Unit: 500 mg
• Quantity Unit: STK