NAMPT activator-6, CAS 2237267-86-4

Product Description: NAMPT activator-6 is a NAMPT activator, a regulatory molecule for the optical control system of NAMPT and NAD+. NAMPT activator-6 can be used to design efficient photoswitchable proteolysis-targeting chimeras (PS-PROTACs) to achieve up-down reversible regulation of NAMPT and NAD+ in a light-dependent manner and reduce the toxicity associated with inhibitor-based PS-PROTACs. PS-PROTAC can be used to achieve antitumor activity, NAMPT, and NAD+ modulation in vivo via optical manipulation[1].

Formula: C17H21N5O3S

References: [1]Cheng J, et al. Photoswitchable PROTACs for Reversible and Spatiotemporal Regulation of NAMPT and NAD. Angew Chem Int Ed Engl. 2024 Mar 18;63(12):e202315997.

CAS Number: 2237267-86-4

Molecular Weight: 375.45

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: NAMPT

• SKU: MEXHY-163445-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-163445-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK