Product Description: Nav1.7 blocker 1 (example 41) is a Na+ channel (Nav) blocker with an IC50 value of 0.037 μM. Nav1.7 blocker 1 can be used for the study of pain, including neuropathic pain, postoperative pain, inflammatory pain, and so on[1].
Formula: C22H21FN4O4
References: [1]Chiyou Ni, et al. Pyrimidines as sodium channel blockers. WIPO. Patent. WO2013030665. 2013-03-07
CAS Number: 1426336-36-8
Molecular Weight: 424.42
Research Area: Inflammation/Immunology; Neurological Disease
Solubility: 10 mM in DMSO
Target: Sodium Channel