NDT-19795, CAS 2272917-12-9

Product Description: NDT-19795 is an effective inhibitor of the NLRP3 inflammasome with an IC50 value of 66 nM in the PBMC method and 4.7 μM in the WB method. NDT-19795 is a carboxylic acid-active substance that can be converted from NT-0796 (HY-156438) within cells. NDT-19795 can be used for the study of neurological diseases[1].

Formula: C20H21N3O4

References: [1]Harrison D, et al. Discovery of Clinical Candidate NT-0796, a Brain-Penetrant and Highly Potent NLRP3 Inflammasome Inhibitor for Neuroinflammatory Disorders. J Med Chem. 2023;66(21):14897-14911.

CAS Number: 2272917-12-9

Molecular Weight: 367.40

Research Area: Neurological Disease

Solubility: 10 mM in DMSO

Target: NOD-like Receptor (NLR)

• SKU: MEXHY-158024-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-158024-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK