Nedosiran (sodium), CAS 2247026-22-6

Product Description: Nedosiran sodium is a GalNAc-dsRNA conjugate designed to inhibit production of the hepatic lactate dehydrogenase (LDH) enzyme.

Applications: Metabolism-sugar/lipid metabolism

Formula: N/A

References: [1]Kevin Shee, et al. Nedosiran Dramatically Reduces Serum Oxalate in Dialysis-Dependent Primary Hyperoxaluria 1: A Compassionate Use Case Report. Urology.2021 Oct;156:e147-e149./[2]Gema Ariceta, et al. Hepatic Lactate Dehydrogenase A: An RNA Interference Target for the Treatment of All Known Types of Primary Hyperoxaluria. Kidney Int Rep. 2021 Feb 3;6(4):1088-1098./[3]Thomas A Forbes, et al. Therapeutic RNA interference: A novel approach to the treatment of primary hyperoxaluria. Br J Clin Pharmacol. 2021 May 22.

CAS Number: 2247026-22-6

Molecular Weight: 22183.60

Research Area: Others

Solubility: H2O : 100 mg/mL (ultrasonic)

Target: Lactate Dehydrogenase

• SKU: MEXHY-132606A-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-132606A-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK