Neuropeptide W-30 (human), CAS 383415-80-3

Product Description: Neuropeptide W-30 (human) is an important stress mediator in the central nervous system that modulates the hypothalamus-pituitary-adrenal (HPA) axis and sympathetic outflow. Neuropeptide W-30 (human) is an endogenous ligand for the two structurally related orphan G-protein-coupled receptors (GPCRs) GPR7 and GPR8. Neuropeptide W-30 (human) activates and binds to both GPR7 and GPR8 at similar effective doses[1][2][3].

Formula: C165H249N49O37S

References: [1]Makoto Kawasaki, et al. Centrally administered neuropeptide W-30 activates magnocellular neurosecretory cells in the supraoptic and paraventricular nuclei with neurosecretion in rats. J Endocrinol. 2006 Aug;190(2):213-23./[2]Nan-Shou Yu, et al. Effects of intracerebroventricular administration of neuropeptide W30 on neurons in the hypothalamic paraventricular nucleus in the conscious rat. Neurosci Lett. 2007 Mar 26;415(2):140-5./[3]Yukio Shimomura, et al. Identification of neuropeptide W as the endogenous ligand for orphan G-protein-coupled receptors GPR7 and GPR8. J Biol Chem. 2002 Sep 27;277(39):35826-32.

CAS Number: 383415-80-3

Molecular Weight: 3543.11

Research Area: Neurological Disease

Solubility: 10 mM in DMSO

Target: Others

• SKU: MEXHY-P10287-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P10287-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK