NH2-C4-NH-Boc, CAS 68076-36-8

Product Description: NH2-C4-NH-Boc (compound 15) is a PROTAC linker, which refers to the Alkyl/ether composition. NH2-C4-NH-Boc can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Applications: Cancer-programmed cell death

Formula: C9H20N2O2

References: [1]Jiang F, et al.Discovery of novel small molecule induced selective degradation of the bromodomain and extra-terminal (BET) bromodomain protein BRD4 and BRD2 with cellular potencies.Bioorg Med Chem. 2020 Jan 1;28(1):115181.

CAS Number: 68076-36-8

Molecular Weight: 188.27

Compound Purity: 99.98

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)/H2O : 100 mg/mL (ultrasonic)

Target: PROTAC Linkers

• SKU: MEXHY-40178-10G
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-40178-10G
• Green Labware: No
• Package Unit: 10 g
• Quantity Unit: STK