NIC-12, CAS 2409826-23-7

Product Description: NIC-12 is a potent NLRP3 inhibitor. NIC-12 selectively reduces circulating IL-1ß levels in the LPS-endotoxemia mice model. NIC-12 inhibits NLRP3 inflammasome activation in mouse macrophages[1].

Formula: C22H28ClN5O2S

References: [1]Vande Walle L, et al. Novel chemotype NLRP3 inhibitors that target the CRID3-binding pocket with high potency. Life Sci Alliance. 2024 Mar 22;7(6):e202402644.

CAS Number: 2409826-23-7

Molecular Weight: 462.01

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: NOD-like Receptor (NLR)

• SKU: MEXHY-158093-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-158093-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK