NLRP3-IN-33

Product Description: NLRP3-IN-33 (Compound 12o) is a blood-brain barrier permeable inhibitor of AChE and BChE, with IC50 values of 1.02 μM and 7.03 μM against hAChE and hBChE respectively. NLRP3-IN-33 possesses antioxidant, anti-inflammatory, and metal chelating activities, making it a potential candidate for research in Alzheimer's disease (AD)[1].

Formula: C21H19N3O5

References: [1]Singh G, et al. Design, Synthesis, and Biological Evaluation of Ferulic Acid Template-Based Novel Multifunctional Ligands Targeting NLRP3 Inflammasome for the Management of Alzheimer's Disease. ACS Chem Neurosci. 2024;15(7):1388-1414.

Molecular Weight: 393.39

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Cholinesterase (ChE);Reactive Oxygen Species

• SKU: MEXHY-162402-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-162402-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK