NLRP3-IN-34, CAS 1392502-55-4

Product Description: NLRP3-IN-34 (Compound T10) is an inhibitor for NLRP3 inflammasome. NLRP3-IN-34 inhibits ROS production, NLRP3 inflammasome-dependent IL-1β production (IC50 is 0.48 μM in cells J774A.1), and inhibits pyroptosis. NLRP3-IN-34 exhibits anti-inflammatory activity against DSS-induced peritonitis[1].

Applications: COVID-19-immunoregulation

Formula: C26H22O6

References: [1]Chen H, et al., Design, synthesis and biological evaluation of tanshinone IIA derivatives as NLRP3 inflammasome inhibitors. Bioorg Med Chem Lett. 2024 May 15;104:129725.

CAS Number: 1392502-55-4

Molecular Weight: 430.45

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: NOD-like Receptor (NLR)

• SKU: MEXHY-158111-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-158111-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK