NMD670, CAS 2354321-33-6

Product Description: NMD670 is an orally active partial inhibitor of the skeletal muscle-specific chloride channel ClC-1. NMD670 increases muscle excitability in response to movement commands, enhances neuromuscular transmission, restores muscle function and improves muscle mobility. NMD670 has a favorable safety profile and improves muscle function in rats in a MG rat model[1].

Applications: Neuroscience-Neuromodulation

Formula: C12H10BrNO4

References: [1]Skov M, et al. The ClC-1 chloride channel inhibitor NMD670 improves skeletal muscle function in rat models and patients with myasthenia gravis. Sci Transl Med. 2024 Mar 20;16(739):eadk9109.

CAS Number: 2354321-33-6

Molecular Weight: 312.12

Compound Purity: 99.60

Research Area: Others

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Chloride Channel

• SKU: MEXHY-158183-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-158183-50
• Package Unit: 50 mg
• Quantity Unit: STK