Product Description: Nω-Propyl-L-arginine (N-omega-Propyl-L-arginine) hydrochloride is a potent, competitive, and highly selective inhibitor of neuronal nitric oxide synthase (nNOS), with a Ki of 57 nM. Nω-Propyl-L-arginine hydrochloride displays a 149-fold selectivity for nNOS over endothelial NOS (eNOS)[1][2].
Applications: Neuroscience-Neuromodulation
Formula: C9H21ClN4O2
References: [1]Zhang HQ, et al. Potent and selective inhibition of neuronal nitric oxide synthase by N omega-propyl-L-arginine. J Med Chem. 1997 Nov 21;40(24):3869-70./[2]Klamer D, et al. The neuronal selective nitric oxide synthase inhibitor, Nomega-propyl-L-arginine, blocks the effects of phencyclidine on prepulse inhibition and locomotor activity in mice. Eur J Pharmacol. 2004 Oct 25;503(1-3):103-7.
CAS Number: 2321366-46-3
Molecular Weight: 252.74
Compound Purity: 98.28
Research Area: Neurological Disease
Solubility: H2O : 25 mg/mL (ultrasonic;warming)/DMSO : 25 mg/mL (ultrasonic;warming)
Target: NO Synthase
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