Product Description: NSC 185058 is an inhibitor of ATG4B, a major cysteine protease. Inhibition of ATG4B using NSC 185058 markedly attenuates autophagic activity[1].
Applications: Neuroscience-Neuromodulation
Formula: C11H9N3S
References: [1]Huang T, et al. MST4 Phosphorylation of ATG4B Regulates Autophagic Activity, Tumorigenicity, and Radioresistance in Glioblastoma. Cancer Cell. 2017 Dec 11;32(6):840-855.e8.
CAS Number: 39122-38-8
Molecular Weight: 215.27
Compound Purity: 99.52
Research Area: Cancer
Solubility: DMSO : ≥ 125 mg/mL
Target: Atg4;Autophagy