Nurr1 agonist 2, CAS 742058-34-0

Product Description: Nurr1 agonist 2 (Compound 7) is a Nurr1 agonist (EC50: 0.07 μM). Nurr1 agonist 2 binds to the recombinant Nurr1 ligand binding domain (LBD) with a Kd value of 0.14 μM. Nurr1 agonist 2 increases the Nurr1-regulated genes tyrosine hydroxylase (TH) and vesicular amino acid transporter 2 (VMAT2) mRNA expression[1].

Formula: C18H14O3S

References: [1]Ballarotto M, et al.De Novo Design of Nurr1 Agonists via Fragment-Augmented Generative Deep Learning in Low-Data Regime. J Med Chem. 2023 Jun 22;66(12):8170-8177.

CAS Number: 742058-34-0

Molecular Weight: 310.37

Compound Purity: 99.27

Research Area: Others

Solubility: DMSO : 20.83 mg/mL (ultrasonic)

Target: Nuclear Hormone Receptor 4A/NR4A

• SKU: MEXHY-W677684-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W677684-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK