NZ-97

Product Description: NZ-97 is an inhibitor for dipeptidyl peptidase 4 (DPP4) with an IC50 of 18 nM. NZ-97 exhibits a low initial plasma exposure with Cmax of 0.13 µM, which is eliminated in 8 h. NZ-97 ameliorates damage in the Lipopolysaccharides (HY-D1056)-induced lung injury and Bleomycin (HY-108345)-induced lung fibrosis in mice model[1].

Applications: COVID-19-immunoregulation

Formula: C43H67N5O9

References: [1]Shao S, et al., Pharmacological expansion of type 2 alveolar epithelial cells promotes regenerative lower airway repair. Proc Natl Acad Sci U S A. 2024 Apr 16;121(16):e2400077121.

Molecular Weight: 798.02

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: Dipeptidyl Peptidase

• SKU: MEXHY-158315-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-158315-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK