Product Description: OB-24 is a potent inhibitor of heme oxygenase-1 (HO-1). Heme oxygenase-1, a member of the heat shock protein family, plays a key role as a sensor and regulator of oxidative stress. OB-24 significantly inhibited cell proliferation in vitro and tumor growth and lymph node/lung metastases in vivo. OB-24 has potential for the research of advanced prostate cancer (PCA)[1].
Applications: Cancer-programmed cell death
Formula: C15H18BrClN2O2
References: [1]Alaoui-Jamali MA, et al. A novel experimental heme oxygenase-1-targeted therapy for hormone-refractory prostate cancer. Cancer Res. 2009;69(20):8017-8024.
CAS Number: 939825-12-4
Molecular Weight: 373.67
Compound Purity: 98.03
Research Area: Cancer
Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 80°C)