Product Description: ODN 1982 sodium is a unmethylated oligodeoxyribonucleotide (ODN) with no CpG motif, and can be used to prepare DNA vaccines. ODN 1982 sodium inhibits R-848 signaling. ODN 1982 sequence: 5’-tccaggacttctctcaggtt-3’[1][2].
Applications: COVID-19-immunoregulation
Formula: N/A
References: [1]Tudor D, et al. TLR9 pathway is involved in adjuvant effects of plasmid DNA-based vaccines. Vaccine. 2005 Jan 26;23(10):1258-64./[2]Jurk M, et al. Modulating responsiveness of human TLR7 and 8 to small molecule ligands with T-rich phosphorothiate oligodeoxynucleotides. Eur J Immunol. 2006 Jul;36(7):1815-26.