Osimertinib, CAS 1421373-65-0

Description: Osimertinib (AZD-9291) is an EGFR third-generation inhibitor that inhibits the T790M resistance mutation produced by second-generation EGFR inhibitors with irreversible and oral activity. Osimertinib has antitumor activity for the treatment of EGFR-mutated non-small-cell lung cancer.

CAS Number: 1421373-65-0

Formula: C28H33N7O2

Molecular Weight: 499,61

References: Hirano T, et al. Pharmacological and Structural Characterizations of Naquotinib, a Novel Third-Generation EGFR Tyrosine Kinase Inhibitor, in EGFR-Mutated Non-Small Cell Lung Cancer. Mol Cancer Ther. 2018 Apr;17(4):740-750.

• SKU: TGMT2490-10mg
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T2490-10mg
• Package Unit: 10 mg
• Quantity Unit: STK