OTUB2-IN-1

Product Description: OTUB2-IN-1, a specific inhibitor of OTUB2 (KD: ~12 μM), reduces PD-L1 protein expression in tumor cells and inhibits tumor growth by promoting robust intra-tumor infiltration of cytotoxic T lymphocytes (CTL) [1].

Applications: COVID-19-anti-virus

Formula: C19H18N2O6S2

References: [1]Ren W et al. Pharmaceutical targeting of OTUB2 sensitizes tumors to cytotoxic T cells via degradation of PD-L1. Nat Commun. 2024 Jan 2;15(1):9.

Molecular Weight: 434.49

Compound Purity: 98.79

Research Area: Cancer; Inflammation/Immunology

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: Deubiquitinase

• SKU: MEXHY-160768-100
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-160768-100
• Green Labware: No
• Package Unit: 100 mg
• Quantity Unit: STK