Product Description: OXA-06 hydrochloride is an ATP-competitive ROCK inhibitor that blocks anchorage-dependent growth and invasion of non-small cell lung cancer cell lines. OXA-06 hydrochloride inhibits cofilin phosphorylation but does not stimulate apoptosis[1].
Applications: Cancer-Kinase/protease
Formula: C21H20Cl2FN3
References: [1]Vigil D, et al. ROCK1 and ROCK2 are required for non-small cell lung cancer anchorage-independent growth and invasion. Cancer Res. 2012 Oct 15;72(20):5338-47.
CAS Number: 1825455-91-1
Molecular Weight: 404.31
Compound Purity: 99.89
Research Area: cancer
Solubility: DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C)